Which of the following describes a situation when the body reacts oppositely to a drug's effects?

Experiencing a withdrawal describes a situation where the body reacts oppositely to a drug's effects. When a person has been using a substance regularly and suddenly stops or reduces their intake, they may experience withdrawal symptoms. These symptoms occur because the body has become accustomed to the presence of the drug, leading to physiological adaptations. As a result, when the drug is no longer available, the body can react in a way that is opposite to the drug's effects, causing discomfort or negative physical and psychological symptoms.

For instance, if a person has been using a sedative drug that depresses the central nervous system, withdrawal might lead to symptoms such as anxiety, agitation, or seizures, which are contrary to the calming effects the drug provided. This phenomenon highlights the body's ability to adjust to the drug's influence, and upon its absence, to exhibit a rebound effect.

In contrast, developing a tolerance refers to the body's progressive adaptation to a drug, requiring higher doses to achieve the same effect, which does not signify an opposite reaction but rather a diminished response to the drug. Increased drug sensitivity indicates a heightened response to a drug, rather than an opposite reaction. Achieving maximum effect refers to reaching the peak efficacy of a drug's action, which would